![]() ![]() Treat symptomatically may recur once treatment is stopped. Stevens-Johnson syndrome, toxic epidermal necrolysis, or erythema multiforme may develop. Discontinue furosemide at first sign of rash may be life-threatening. Assess patient for skin rash frequently during therapy.Hearing loss is most common after rapid or high-dose IV administration in patients with decreased renal function or those taking other ototoxic drugs. Audiometry is recommended for patients receiving prolonged high-dose IV therapy. ![]() Assess patient for tinnitus and hearing loss.Potassium supplements or potassium-sparing diuretics may be used concurrently to prevent hypokalemia. Patients taking digoxin are at increased risk of digoxin toxicity because of the potassium-depleting effect of the diuretic. Assess patients receiving digoxin for anorexia, nausea, vomiting, muscle cramps, paresthesia, and confusion.Assess falls risk and implement fall prevention strategies. Geri: Diuretic use is associated with increased risk for falls in older adults.Monitor frequency of prescription refills to determine compliance in patients treated for hypertension. Monitor BP and pulse before and during administration.Notify health care professional if thirst, dry mouth, lethargy, weakness, hypotension, or oliguria occurs. Monitor daily weight, intake and output ratios, amount and location of edema, lung sounds, skin turgor, and mucous membranes. Availability (generic available) Availability (generic available) PO (Adults) : 40 mg twice daily initially (when added to regimen, ↓ dose of other antihypertensives by 50%) adjust further dosing based on response. IM IV (Neonates) : 1–2 mg/kg/dose every 12–24 hr. IM IV (Children) : 1–2 mg/kg/dose every 6–12 hr Continuous infusion– 0.05 mg/kg/hr, titrate to clinical effect. IM IV (Adults) : 20–40 mg, may repeat in 1–2 hr and ↑ by 20 mg every 1–2 hr until response is obtained, maintenance dose may be given every 6–12 hr Continuous infusion– Bolus 0.1 mg/kg followed by 0.1 mg/kg/hr, double every 2 hr to a maximum of 0.4 mg/kg/hr. PO (Neonates) : 1–4 mg/kg/dose 1–2 times/day. PO (Children >1 mo) : 2 mg/kg as a single dose may be ↑ by 1–2 mg/kg every 6–8 hr (maximum dose = 6 mg/kg). Hypertension– 40 mg twice daily initially (when added to regimen, ↓ dose of other antihypertensives by 50%) adjust further dosing based on response Hypercalcemia– 120 mg/day in 1–3 doses. Maintenance doses may be given once or twice daily (doses up to 2.5 g/day have been used in patients with HF or renal disease). PO (Adults) : 20–80 mg/day as a single dose initially, may repeat in 6–8 hr may ↑ dose by 20–40 mg every 6–8 hr until desired response. ![]()
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